If you can't get rid of the ball quickly, you need to change your gameplan.
NFL coaches are so stupid these days... like Mike Tice got shredded an entire game with the screen pass. He never once adjusted. And also, against the Rams, Leonard Little lined up so far outside of the Tackle that there was no chance to stop him. Did he put a TE over there, or a FB in the backfield to stop him? No. He just allowed the sacks and complained that the Line didn't do its job.
And Minnesota just released their #2 receiver behind Moss last year, so MN knows how to pass to a WR without a second option. If the Pats and Eagles can make it that far with no valid receiving threat, the Bills had no excuse to miss the playoffs. No #2?