This year:
Strong Bads Cool Game for Attractive People
Sim City Creator
De Blob
Wario Land: The Shake Dimension
Skate It (maybe, if it sounds good and I can afford a balance board)
Sonic Unleashed
Whenever they get released:
Animal Crossing: City Folk
Pikmin 3
New Mario/Zelda
GTA: CTW
GTA Wii (That Reggie guy wants it and if the DS game does well, we'll probably see this)
Spore Wii (which is unofficially officially in the very early stages of development but is officially officially not.)
I'll get Spore one way or another. My PC wont run the demo so I have to use a family members laptop. If they let me use it for the game, then I might buy it. If not, I'll have to just wait for a Wii version and hope it isn't a mutant version like the DS Spore or a bare bones version like every Sim game ever on a console.
No decent DS games to be seen anytime soon

Still no real idea how GTA will turn out on DS, so I can't be sure.