Last year LSU (lousiana-state, SEC) beat Ohio State (Big-Ten) in the National title. And before that it was Florida (also SEC) beating OHio State in the National championship.
The SEC is pretty clearly the dominant conference the last few years, but this year the Big-12 will be strong.
Michigan is rebuilding currently, so it is only really Ohio State and Wisconsin in the Big-10. USC (southern california) is always dominant from the Pac-10, they always have a shot at the national championship. (USC had Carson Palmer and then MAtt Leinart at QB back to back a few years ago

)
UH, ACC is REALLY weak this year. Like embarrassingly weak. IF Clemson doesn't make the ACC title game it would be an embarrassment. VA TECH is the other ACC power this year and you saw them lose to East Carolina (an unkown) yesterday.
The Big East really shouldn't be a major conference anymore
UH yeah, let me just answer some questions I guess