Eternal Darkness although it is possible now that Silicon Knights got a $4 million grant from Canada and Nintendo does have that Vitality Sensor they could use to create new sanity moments (Nintendo owns the Sanity effects from the 1st game).
Conkers Bad Fur Day, WWF No Mercy (more for keeping the engine than being a true sequel), and The Punisher (2005 version and not NES/Genesis version).
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