Crawford is going to be a big blow, but luckily Desmond Jennings is probably going to come up to replace him.
You have to figure though, that in 2-3 years a rotation of Price, Garza, Niemen, Davis, and Hellickson will be absolutely ridiculous. They can deal James Shields for a bat really, and still probably have the best rotation in the bigs.
That is, unless the Yankees get Cliff Lee