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Adobe Reader is ok if you disable the constant update reminder. Photoshop is heavy on resources but it's normal for what it does. iTunes depends on what you use it for. If it's just as a music player, it's unnecessarily hard on your resources, but if you use it to manage your library, download music, etc, then it's ok. Nero has a shitload of stuff you don't need that gets installed with it, but it won't eat up CPU or RAM.
McAfee is also kind of ridiculously heavy for something so mainstream.
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