The Niners/Ravens SB has to now be solidified as the worst loss in franchise history. When it first happened it was pretty much "well that's a heartbreaker for them, but they are building a really great franchise and I could totally see them finishing the job in the next year or two to make up for it".
But then you had the NFC Title game the next year, Sherman basically mocking them en route to a title win, a subpar 2014 and then the entire team wound up getting dismantled with Harbaugh leaving and players retiring en masse.
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