I don't think there is, tbh. I have to see if there's a difficulty setting, as I've been playing for quite awhile and don't remember. It would probably be easier in Skyrim to play it that way as food and water are more plentiful.
I tried Fallout like that and didn't like it. Maybe if I play through it once, then go back and try playing in Hardcore Mode, I might enjoy it.
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