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I redid the game and somehow lost Jack (couldn't get my paragon points up high enough to get her to be loyal. Thought having her with me would have saved her life.)
Here are the things I believe will effect our chances at defeating the reapers:
1. keeping the work towards curing the Krogan genophage
2. infecting the geth with the virus Legion re-wrote
3. Keeping the collector base for Cerberus
The more Krogan and Geth we have to fight the Reapers the better. The collector base seems to be more of an unknown. Will keeping it come back to bite us in the ass?
Would you work with the devil if it meant saving the galaxy?
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